DiscoveryGate

About DiscoveryGate

DiscoveryGate provides a wealth of information on chemical compounds, reactions, and synthetic methodologies. It includes:

• Beilstein (1771-present)

A primary resource for finding structures, reactions, and data for organic substances.

• Gmelin (1772-present)

Contains data and reaction information for organometallic and inorganic substances.

• MDL Comprehensive Medicinal Chemistry (1900-present)

3D models and biochemical properties for pharmaceutical compounds.

• MDL Drug Data Report

Data on newly launched or developmental drugs.

• National Cancer Institute Database

NCI's CAS Registry, Plated Compounds, AIDS and Cancer databases.

• MDL Metabolite Database

A compilation of xenobiotic transformations and metabolic schemes.

• MDL Toxicity Database

Toxicological data from worldwide sources such as RTECS and GENE-TOX.

• MDL Available Chemicals Directory

Pricing and supplier information for commercially available chemicals.

• MDL Screening Compounds Directory

Supplier data for high-throughput screening.

• ChemInform Reaction Library

Reaction data from the chemical literature 1900 to present with an emphasis on synthesis.

• Derwent Journal of Synthetic Methods

Updated annually, a selection of chemical reaction information from over 150 journal and patent sources.

• ORGSYN Database

Online version of Organic Syntheses (1921-present). Preparations that have been tested and verified by chemists in independent laboratories.

• MDL Reference Library of Synthetic Methodology

Compilation of synthetic methods published through 1991. Includes Comprehensive Heterocyclic Chemistry (through 1983) and Theilheimer's Synthetic Methods of Organic Chemistry (1946-1981).

• MDL Solid-Phase Organic Reactions (1963-present)

Covers solid-phase reactions from over 150 chemistry journals and selected patent sources.

Due to license restrictions, DiscoveryGate is available only to current UT-Knoxville students, faculty and staff.

System Requirements

• PC users:

Windows 2000 or XP; IE 6.0; Java Runtime Environment (JRE) 1.4.2_06 (installs automatically)

• Mac users:

Mac 10.4 or higher; Safari 2.0

Installation

Note: Be sure to allow pop-ups for this site. You must have administrative privileges or be authorized by your system administrator to install DiscoveryGate software on your computer.

• PC users

1. Open Internet Explorer.
2. Go to the DiscoveryGate web site.
3. If this is your first visit, the site will automatically install JRE 1.4.2_06 (Java Runtime Environment). The browser may shut down after installation. Just reopen, return to the site, and continue.
4. Click on the Download Software tab.
5. Click on the Download button, and save the installer to your desktop.
6. Close all browsers. Then double-click on the installer, and follow instructions.

• Mac Users

1. Open Safari.
2. Go to the DiscoveryGate web site.
3. If this is your first visit, the site will automatically install JRE 1.4.2_06 (Java Runtime Environment).
4. Follow the directions.

CrossFire Commander

By January 31, 2006, users will need to change the client host settings of their desktop installation of Beilstein CrossFire Commander. To change your client setting:

1. Open CrossFire Commander.
2. Click on Options/Define Server Profiles.
3. Click on Edit.
4. Enter crossfire-acad.mdl.com in the host address.
5. Be sure the Forget User ID/Password box is unchecked, else you will be asked for the password the next time you log in.